The know error® system utilizes bar coding, forensic principles and DNA Specimen Provenance Assay (DSPA) testing to confirm that surgical biopsy samples being evaluated belong exclusively to the patient being diagnosed and further confirm tissue specimens are free from contamination which can otherwise confound Biomarker Test results.
By applying the same forensic principles used in law enforcement and criminal investigation to compare and match DNA profiles. Strand Diagnostics’ DSPA test (or DNA match) uses a buccal swab-to-biopsy tissue comparison to rule out the possibility of cancer misdiagnosis due to specimen contamination errors and confirms the cancer diagnosis is ascribed to the correct patient.
The patented know error system is increasingly becoming the standard of care for healthcare centers throughout the U.S. and can easily be integrated within any medical practice, surgery center, hospital facility, and/or pathology lab to deliver enhanced patient safety and diagnostic accuracy to the biopsy process.
Documented studies confirm that occult Specimen Provenance Complications (SPCs) happen at a rate of up to 3.5% which can result in a cancer diagnosis being assigned to the wrong patient; or in the case of Biomarker Testing admixtures (a specimen containing another’s DNA) can confound the test results and lead to incorrect conclusions and therapy. Further study analysis documents the societal economic burden of healthcare expenditures associated with undetected SPCs to exceed $880 million annually.
Rule out specimen contamination and patient misidentification errors before diagnosis and treatment with the know error system, the only solution to mitigate the clinical and economic impact of specimen provenance complications among surgical biopsies.