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Case Studies

Provenance of Unknown Tissue in Mixed Sample Jar Determined Through DNA Testing

Upon discovering that two different tissue types had been placed in the same biopsy jar, a large pathology services provider contacted Know Error to help determine the provenance of each specimen. As one of the tissues was positive for cancer, it was especially important to identify which patient was in need of treatment in a prompt manner. Read the full case. | PDF (442KB)

 

DNA Testing Confirms Identity of Transposed Breast Specimens

After a female patient underwent a partial mastectomy as treatment for invasive ductal carcinoma, the pathologist discovered there were no cancer cells present in her extracted breast tissue. Know Error was consulted to investigate the situation and help determine whether the patient actually had cancer. Read the full case. | PDF (311KB)

 

Prostate Cancer Misdiagnosis Identified by DNA Specimen Provenance Assignment Testing

In this case, prospective use of the know error® system identified a prostate cancer misdiagnosis caused by a biopsy sample misidentification. Proper identity was assigned to the transposed specimens before any inappropriate treatment took place for either patient. Read the full case. | PDF (352KB)

 

DNA Specimen Provenance Assignment Testing Clarifies Identity of Mixed Prostate Biopsy Samples

When a physician’s office error resulted in multiple prostate specimens being placed in the same biopsy jars, Know Error was contacted to help determine proper origin of all the samples to ensure the appropriate patients could be notified of their diagnoses. Read the full case. | PDF (246KB)

 

DNA Testing Verifies Identity of Mislabeled Prostate Specimens

Through prospective use of the know error® system, a positive/positive prostate biopsy switching error was identified at a practice’s in-house laboratory. Although both patients were diagnosed with cancer, it was still important to assign the proper specimen to each person as treatment options are often determined by tumor grade, volume, location, etc. Read the full case. | PDF (680KB)